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Advaxis Brand Drug On Clinical Hold

Author Elsie Aniekwe

The clinical-stage biotechnology company Advaxis, which as stated on the company’s website focuses on developing cancer immunotherapies that use the body’s natural immune system to redirect the immune response to kill cancer, has come under federal scrutiny following the death of a clinical trial patient..

FDA Clinical Hold Details

After Advaxis sent a safety report to the FDA that mentioned a patient’s death, clinical mid-stage trials of the experimental axalimogene filolisbac drug were put on hold.

According to Reuters, the patient was admitted to the hospital and was undergoing treatment for an aggressive stage cervical cancer. Advaxis claims, however, that the patient died as a result of the ongoing disease and that the drug axalimogene filolisbac played no part.

According to Advaxis, the FDA has requested to be shown more proof that the experimental drug did not cause the patient’s death.

HPV and Cervical Cancer Details

The following information was provided by

  • HPV or Human Papilloma Virus is a group of more than 200 related viruses that can lead to types of cancer, one being cervical cancer.
  • Cervical cancer occurs when abnormal cells on the cervix grow rapidly.
  • HPV is sexually transmitted through skin and mucous membranes.
  • HPV types 16 and 18 cause just about every case of cervical cancer.

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One Dead in Waxahachie Trucking Accident

Author Jarod Cassidy

An accident in Waxahachie, Texas involving two vehicles has lead to the death of one man, several news stations reported.

Details of the Fatal Accident

Early Tuesday morning police and emergency responders arrived at Howard Road, near Lake Waxahachie Dam.

A Nissan sedan, heading northbound on Howard Road, came around a corner at a high rate of speed, lost control and slid into the southbound lane striking an international lumber truck.

The driver of the sedan died at 9:09 a.m. due to multiple blunt force injuries. Precinct 2 Justice of the Peace Jackie Miller Jr. reported that there was no indication of drug or alcohol use.

Officials have yet to release the name of the driver, pending approval of the family members. Officer David Bittle, of the Waxahachie Police Department said the driver of the lumber truck was uninjured.

Miller has ordered an autopsy of the body at the Dallas Medical Examiner’s Office. The accident is still under investigation.

Texas Auto Accident Attorney

The following information was provided by the Texas Department of Transportation (TxDOT):

  • 3,534 people were killed in auto accident in Texas in 2014 – a 2.16-percet increase over the 3,408 deaths recorded in 2013.
  • An additional 237,941 people were injured in auto accidents in 2014 with 17,152 people suffering sustaining incapacitating injuries.
  • A reportable crash occurred every 66 seconds in Texas in 2014.

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5-Year-Old Abandoned On Daycare Bus

Author Abi Reyes

Austin authorities are investigating reports that a 5-year-old was abandoned on a daycare bus for hours in the heat.

Father Finds Son Alone in Hot Daycare Bus

According to KEYE News, a family claims their five-year-old son, Om Dave, was abandoned in a hot daycare bus for three hours Friday evening. When the Om’s father went to pick him up from Xplor daycare after work, he was horrified that no one knew where his son was.

After 15 minutes of searching, the daycare staff found the boy alone in the bus.

The little boy says that when he saw that the bus was empty he tried to open the doors and kick the windows but could not get out. The 5-year-old’s father says Om either fell asleep or passed out from heat exhaustion.

Om's parents have filed a report with the police and are pulling him out of Xplor daycare.

Vehicular Heat Stroke Facts

The following information was provided by

  • Even if a vehicle has its windows cracked, the temperature inside a car can escalate to more than 125 degrees within minutes. 80-percent of the temperature increase will occur within the first 10 minutes.
  • A child’s body overheats 3-5 times faster than adults. Instances of child heatstroke have occurred in cares in temperatures as low as 60 degrees.
  • In 50-percent of child vehicular heatstroke deaths, the child’s guardian unknowingly left them in the vehicle.

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