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ACE Inhibitors

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The Dangers of ACE Inhibitors

Angiotensin-Converting Enzyme (ACE) inhibitors are a class of medications used to treat high blood pressure (hypertension), congestive heart failure, and renal disease by relaxing blood vessels and increasing blood flow to the heart. They have been on the market for more than 25 years and are one of the most widely prescribed drugs classes in the United States.

ACE Inhibitors and Birth Defects

ACE inhibitors have long been associated with increased risks to the fetus during the second and third trimesters of pregnancy, as the fetal kidneys are developing. Taking ACE inhibitors in the late stages of pregnancy can cause:

  • skull deformities
  • kidney failure
  • lung problems
  • fetal death

In 2006, the New England Journal of Medicine published an article stating that taking ACE inhibitors during pregnancy, even during the first trimester, can cause birth defects. The study found that infants whose mothers had taken ACE inhibitors during their first trimester were twice as likely to be born with congenital malformations affecting the heart, brain and nervous system.

FDA Black Box Warning

ACE inhibitors currently bear a black box warning about their dangers in the later stages of pregnancy and the FDA warns women to stop taking ACE inhibitors as soon as pregnancy is detected.

ACE Inhibitor Brands
  • Accupril (Quinapril)
  • Aceon (Perindopril)
  • Altace (Ramipril)
  • Capoten (Catopril)
  • Lotensin (Benazepril)
  • Mavik (Trandolapril)
  • Monopril (Fosinopril)
  • Prinivil, Zestril (Lisinopril)
  • Univasc (Moexipril)
  • Vasotec (Enalapril)
Contact An Experienced ACE Inhibitor Attorney

Thomas J. Henry Injury Attorneys are leaders in the area of drug and product liability litigation. Our Defective Drug and Products Division have extensive knowledge and resources in order to represent our clients efficiently and aggressively. The Defective Drug and Products Division represent a multitude of people who are battling against manufacturers of medical devices and/ or defective pharmaceuticals.

Your choice does matter. If you or a loved one has suffered serious injuries because of an ACE inhibitor, call Thomas J. Henry Injury Attorneys immediately. We are available 24/7, nights and weekends.



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