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Ariad to Resume Sales of Iclusig

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Jarod Cassidy4 years ago

Ariad Pharmaceuticals Inc. will be resuming sales for its leukemia drug, Iclusig, after it was suspended from the U.S. market for blood clot concerns.

Iclusig Linked to Blood Clots

  • Iclusig (ponatinib) was approved last December by the U.S. Food and Drug Administration as part of an accelerated approval process based on a single clinical trial demonstrating a positive patient response.
  • However, post marketing trials showed that patients were at much higher risk of suffering serious side effects including blood clots and heart damage.
  • Ariad announced on December 20, 2013 that sales for Iclusig would resume, but the drug will require an updated boxed warning detailing the new blood clot and cardiovascular problems.

Side Effects of Iclusig

According to may lead to:

  • Fever
  • Anxiety
  • Irregular Heart Beat
  • Seizure
  • Cardiac Arrest
  • Stroke
  • Decreased Vision
  • Loss of blood flow resulting in tissue death and amputation
  • Heart Failure
  • Respiratory Infection
  • Blood Clots
  • Heart Attack
  • Death
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