According to KRIS-TV, the crash occurred around 2:00 am when a Jeep that was traveling in the wrong direction on the Harbor Bridge crashed into an SUV.
Both drivers were taken to Christus Spohn Shoreline in critical condition.
Traffic was stalled in the Southbound lanes as crews cleared the scene of debris.
Police say the accident is still under investigation, though they do believe the wrong-way driver may have been driving under the influence.
The following information was provided by the Texas Department of Transportation (TxDOT):
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