The accident occurred in the Westwood Village Shopping Center at the intersection of Sunset and West Houston.
Police are reporting the man was driving a red jeep at high speed when he crashed into another vehicle. The impact caused the car to collide with three other vehicles.
Police suspect the man may have suffered from a medical condition which caused the wreck. The victim, an unidentified man, was pronounced dead at the hospital.
Following information provided by the Texas Department of Transportation (TxDOT):