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Infection Rate Rising from Prostate Biopsies

Mary Wolff2 years ago

Medscape is reporting the findings of a Swedish study that shows rates of severe infection after transrectal ultrasound-guided (TRUS) prostate biopsy are on the rise.

About the Swedish Biopsy Study

The leaders of the study analyzed the frequency and severity of infectious complications in a cohort of 51,321 men who underwent ultrasound-guided prostate biopsy from 2006 to 2011.

The team found that 3,210 of the men received a prescription for a urinary tract antibiotic in the month after the biopsy, and 54% had the prescription filled in the week following the procedure.  Of all the hospitalizations due to severe infections, 74% of men were hospitalized within a week of the biopsy.  

Men who had already experienced a urinary tract infection prior to a biopsy or suffered from diabetes were more likely to develop one after the procedure.  Men who were hospitalized were at the greatest risk for death due to infection. Out of the cohort, 34 died of a urinary tract infection or sepsis.

Implications of the Study

The study suggests that a biopsy should only be done in patients whose survival chances can be improved with a diagnosis of prostate cancer and also show other signs of prostate cancer.

The study does not recommend a biopsy for men who are at a high risk for infections or men who have life expectancy rates effected by other factors.


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