According to KXAN, the chain reaction accident began when a vehicle driven by 32-year-old Jessica Marciano of Torrington, Connecticut overturned in the eastbound lanes of the interstate.
Marciano escaped the wreckage and was sitting on her vehicle when the car was struck by an approaching tractor-trailer. Marciano was killed in the collision.
The 18-wheeler then veered into the westbound lanes and struck an oncoming car. The driver of the second car, Izaguirre Isael, 54, as well as two of his passengers were pronounced dead at the scne.
The driver of the tractor-trailer was transported to a nearby hospital.
Authorities believe Marciano fell asleep behind the wheel, causing her car to drift and overturn.
The following information was provided by the National Highway Traffic Safety Administration (NTHSA):